NMR metabolomics in cancer research

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as an understanding of the specific characteristics of the cancer metabolic phenotype. The author, Miroslava Cuperlovic-Culf,presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, she begins by examining cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis.In the latter half of the book, Dr. Cuperolovic-Culf looks at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field.